Dr. Christine F. Chaisson

Ph.D. Cellular Biochemistry, George Washington University, Washington, D.C. 1982

Graduate Studies Program, Department of Physiology, L'Ecole de Medicine, Paris, France

B.A. Biology, Boston University, Boston, Mass.

Employment History

2000- 2003 Consultant, specialty in risk assessment, toxicology and risk modelling. Director of LINEA, Inc. and Director of The LifeLine Group

1997-1999 Partner and President of TAS-ENVIRON, specialty in toxicology and risk assessment

1985- 1997 Co-founder and president of Technical Assessment Systems, consulting firm specializing in pesticide risk assessment.

1976 - 1985 Toxicologist at the US Environmental Protection Agency, serving as Chief of Toxicology, specialty in carcinogenicity and mutagenicity, and risk assessment modelling.

Dr. Chaisson is a recognized expert in risk assessment and regulatory strategies for pesticides, food additives and other chemicals in the human environment. She is one of the architects of the first, and also the most recent exposure assessment software models being used in the United States.

Dr. Chaisson was trained as a cellular biochemist, working in molecular biology and basic cellular mechanisms, earning a doctorate from George Washington University. At the Hahnemann Hospital in Philadelphia, she was involved in human cancer therapeutic research, and at the Veterans Administration Hospital in D.C., she did basic research on the chemical mechanisms involved with respiratory function.

Dr. Chaisson began her career in risk assessment when she was recruited to the US Environmental Protection Agency in the Office of Pesticides and Toxic Substances. Before becoming the Acting Chief of Toxicology, she served as the Chief Project Officer for research, overseeing projects at several EPA research facilities as well as the lead toxicologist for risk assessments on many pesticides. At EPA Dr. Chaisson designed and created the first dietary exposure assessment model. She was also the liaison to international regulatory agencies such as AID and WHO.

In 1985, Dr. Chaisson co-founded Technical Assessment Systems (TAS), which became the premier exposure/risk assessment consulting firm internationally. Through TAS, she introduced concepts such as population subgroup specificity, better definition of residues in forms of foods and sources of drinking water, use of human activity patterns and actual chemical usage patterns for more accuracy and relevance in risk assessment models. Her regulatory strategies have been important advances for both industry and government. Through these experiences, Dr. Chaisson has become well versed in the expectations of regulators in the US, UK, Canada, Germany, and European Union. In December of 1998, the acquisition of TAS by ENVIRON Corporation was completed, and Dr. Chaisson became a professional advisor for industry and government agencies on risk assessment approaches and safety evaluation strategies.

Most importantly, Dr. Chaisson is one of three key architects of the new generation of exposure assessment models addressing aggregate and cumulative risk concepts, called LifeLine™. Her special focus on these models has been in the dietary sections-agriculture, food technology, food consumption and food composition.

Dr. Chaisson has been the lead project strategist and risk assessor for several industry entities seeking pesticide registration and compliance with the FQPA and/or international regulatory standards. She serves as a retained consultant for food production companies, chemical companies, government entities and trade associations for performing risk assessments or developing models to aid in that assessment. This work involves an emphasis on US EPA, US FDA, state, Canadian or other international risk assessment approaches and application of analytical and toxicological data to the assessments.

Over the past five years, Dr. Chaisson has collaborated with colleagues to create the most advanced exposure and risk assessment software for considering multiple sources of exposure from one or multiple chemicals over the lifetime (aggregate and cumulative assessment). This model, LifeLine™ is now in use in the US and Canada for pesticide regulatory risk assessment , as well as in a dozen universities as a tool for teaching risk assessment. Dr. Chaisson serves as a Director on the Board of The LifeLine Group, a not-for profit institute dedicated to the development of technically excellent risk assessment tools, and making those tools widely available and applicable to a wide range of stakeholders in the risk assessment practice.

The LifeLine™ models are designed to interface with pharmakokinetic and pharmakodynamic models to better reflect actual dose/effect relationships. Such an interface model has been developed by The LifeLine Group as part of a research project with the American Chemical Council. Other important projects include the careful examination of nutrition studies and food intake studies to better understand the relationships between dietary profiles (or other personal habits) and health status, especially obesity.

The science and social demands on the concept of risk assessment have created a rich opportunity for advances in the technical, political, social and communication arenas. Industries, government and academia are evolving new roles in this process. Dr. Chaisson is devoting her experience to development of sophisticated new software tools to facilitate the technical processes, to be responsive to the traditions of different regulatory authorities, and to assisting industries and government groups to address new health risk issues and paradigms. Her present consulting practice involves both government cooperative agreements and corporate/private consulting.

Dr. Chaisson's skills in communication and visualization of the risk assessment process-and its consequence to society-has attracted many speaking opportunities and positions on policy boards. Dr. Chaisson also serves on the National Council for Arts and Sciences of the George Washington University and the Dean's Advisory Board for the GWU Graduate School of Political Management. She is an advisor to Food Quality magazine.

PUBLICATIONS AND PRESENTATIONS (Partial Listing)

P. S. Price, Conolly, R.B., Chaisson, C.F., Young, J.S., Mathis E.T., Tedder D.T. 2003. Modeling Inter-individual Variation in Physiological Factors Used in PBPK Models of Humans, Critical Reviews in Toxicology Vol. 33, (5): 469-503

Variation in Physiological Factors: Improved Methods: Prediction of Target Tissue Dose, June 2003, American Chemistry Council's Long Range Initiative Annual Science Meeting, Herndon, VA.

P.S. Price, C.F. Chaisson, M. Koontz, C. Wilkes, B. Ryan, D. Macintosh, and P. Georgopoulos, A Comprehensive Chemical Exposure Framework Based on a Nested Loop Approach and a Taxonomy of Longitudinal Change in Exposure Related Parameters. June 2003, American Chemistry Council's Long Range Initiative Annual Science Meeting, Herndon, VA.

FIFRA Scienific Advisory Panel, The LifeLine™ Model Project to Model Aggregate Exposures to Pesticides, Arlington, VA , September 2001

Chaisson, C.F. and Price, P.S., (2001) " Presentation of 4 exposure scenarios in an aggregate risk assessment with LifeLine™", ORD Workshop on Residential Exposure Assessment Models, EPA/ORD, RTP, North Carolina, October, 2001.

Price, P. S., Young, J.S., and Chaisson, C.F., "Assessing Aggregate and Cumulative Pesticide Risks Using a Probabilistic Model", Annals of Occupational Hygiene, 2001 Vol 45, No. 1001, S131-S142.

Chaisson, C.F., "Dietary Model for Aggregate and Cumulative Risk Assessment", International Society of Exposure Assessment, Asilomar, California, October 2000.

Chaisson, C.F., Dietary Exposure-Profiling and LifeLine Assessments" in "Children's Exposure to Toxic Chemicals-Modeling their World to quantify the Risks: Session V", NeuroToxicology 74 (2001) 1-4.

Chaisson, C.F., (1997). "Communicating Differences in Risk Approaches" Environmental Risk Harmonization: Federal and State Approaches to Environmental Hazards in the USA, Edited by M.A. Kamrin. Published by John Wiley & Sons Ltd. Chapter 4, p. 33-39.

Chaisson, C.F., (1997). " 1996 Food Quality Protection Act: What it Means for the Food Chain Industries." Presented at the American Agri-Women 4th Annual Agricultural Issues Symposium Agricultural Trade: A Whole New World, Washington, DC, June.

Chaisson, C.F., Sielken, R.L., Waylett, D.K., (1997) "Why the 99.9th Percentile Goes Bump in the Night, The Fragile Tail in Risk Assessment Distributions: The Dietary Profile Analysis and Food Consumption Data. (To be Published).

Chaisson, C.F., (1997). "Establishing Tolerances (MRLs) in the USA." and "Dietary Risk Assessment for Pesticide Residues within the USA." Presented at the IBC UK Conference on Pesticide Residues in Food and Dietary Risk Assessment, London, June.

Chaisson, C.F., (1997). "Sanitary and Phytosanitary Issues." Presented at the USDA/UAL: Feeding the New Dragons - How to Successfully Export Ag Products to the Emerging Markets of the Pacific Rim Workshop, Long Beach, CA, May.

Chaisson, C.F., (1996). "Communicating Differences in Risk Approaches" Present at IET/MSU Conference on the Harmonization of Federal/State Approaches to Environmental Hazards, East Lansing, MI, June, Environmental Risk Harmonization: Federal and State Approaches to Environmental Hazards in the USA, Edited by M.A. Kamrin. Published in 1997 by John Wiley & Sons Ltd.

Chaisson, C.F., (1996). "Dietary Risk Assessment." Presented at the IBC Conference on Environmental and Human Health Risk Assessments for Agrochemicals, London, July.

Chaisson, C.F., J.S. Douglass, and B.E. Sever (1995). "How will International Food Regulation Affect you/your Business." Presented at the Association for Dressings and Sauces, New Orleans, LA, May.

Chaisson, C.F., C.P. Gaston, H. Michael Wehr, C.B. Sandusky (1995). "Regulatory and Labeling Requirements: Conquering Differences at the Border." Presented at the United Agribusiness League, San Diego, CA, September.

Chaisson, C.F., (1995). "European Policies & Activities in the Chemical Sensitivity Area." Presented at Multiples Chemical Sensitivities: State of the Science Symposium, Baltimore, MD, October.

Petersen, B.J. and C.F. Chaisson (1995). "Simulation Studies in Dietary Exposure Assessment. Presented at the TNO/WHO Dietary Exposure to Contaminants and Additives: Risk Assessment in Europe, The Netherlands, June.

Chaisson, C.F., J.S. Douglass, B.E. Sever (1995). "How Will International Food Regulation Affect You/Your Business?" Presented at the Association of Dressings and Sauces Meeting, New Orleans, LA, May.

Chaisson, C.F. (1995). "Harmonisation of Strategies for Utilizing Available Data on a Pan-European Basis." Presented at ILSI Europe Workshop on Food Additives, Brussels, Belgium, March.

Chaisson, C.F. (1994). "Contemporary Options in Dietary Profile Assessment: Making the Most of What We Know Today and Application to Tomorrow's Needs." Paper presented for the Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin, Berlin, Germany, September.

Chaisson, C.F. (1994). "Pesticide Residues in Processed Foods: A Barrier for Exporting Products to the U.S." Speech presented for the Second National Congress of the Food Industry and Expo - AGTA '94, Guatemala City, Guatemala, April.

Chaisson, C.F. (1993). "Food Safety Debates on Pesticide Raise New Risk Assessment Concepts." Article published in the IFT Toxicology and Safety Evaluation Division Newsletter, Volume 13, Number 1.

Chaisson, C.F. (1993). "Issues on Considering Criteria for Developmental and Reproductive Toxicity. Speech presented at the Proposition 65 DART Identification Committee Public Meeting, Sacramento, CA, October 25.

Chaisson, C.F. (1993). "Emerging Risk Assessment Concepts and Applications to Food Safety Regulatory Process." Paper presented at The Toxicology Forum 1993 Annual European Meeting, Oxford, United Kingdom, September 21-24.

Chaisson, C.F. (1993). "The Regulatory and Public Viewpoint (Emphasis on USA Market)." Presented at the Pesticide in World Food Trade Programme, Bogota, Colombia, August 12.

Chaisson, C.F. (1993). "Food Safety and Health Risk Communications." Speech presentation at the Canadian Dietetic Association 58th Annual Conference, Toronto, Ontario Canada, June 2.

Chaisson, C.F. (1993). "Keeping Good Things Growing." Speech presented at the Canadian Horticultural Council Meeting, Ottawa, Canada, March 7-9.

Professional Memberships:

Society of Risk Assessment
International Society of Regulatory Toxicology and Pharmacology
American Chemical Society
International Society of Exposure Assessment
United Agribusiness League
Institute of Food Technologists

Paul S. Price, M.S.

M.S. Civil Engineering. University of Maryland, 1979

B.A. Chemistry, University of Maryland, 1974

Employment History

2000- Present Director, LINEA, Inc. Director, The LifeLine Group, Inc.

1998 - 2000 Principal Scientist, AMEC Environmental and Energy Services

1996 - 1998 Principal Health Scientist, McLaren/Hart, Inc.

1991 - 1996 Supervising Health Scientist McLaren/Hart, Inc.

1987 - 1991 Staff Leader for Benzene Task Force, American Petroleum Institute (API)

1979 - 1987 Chemist, USEPA, Offices of Drinking Water and Toxic Substances

1976 - 1978 Environmental Research Technician, Maryland Environmental Services,

1974 - 1975 Chemist, W.R. Grace & Company, Inc.

Mr. Price is a recognized leader in the field of human exposure assessment and risk assessment. He is currently project Director for VCCEP Tier 1 Assessments for Benzene, Toluene, Xylene, Ethyl Benzene, and Acetone. This project will develop and present the Tier 1 exposure and risk assessment to VCCEP panels over 2003-2004.

Other recent projects include:

Assessment of cumulative risks for Organophosphorous Pesticides for EPA using LifeLine Software. This project produced a cumulative assessment of pesticide exposures from dietary, tapwater, and residential exposures.

Assessment of exposures from use of an OP pesticide in consumer (pet related) products. This project required the evaluation of exposure to a pesticide active ingredient from use in a number of consumer projects, development of data quality objectives for exposure related research, and the preparation of agency submissions.

Assessment of Non Lethal Weapons. This project will develop models of the intended and unintended effect from the use of non-lethal weapon systems for the U.S. Department of Defense.

Project Director for the Development of a Comprehensive Chemical Exposure Framework. This ongoing project will develop the technical basis for the design of a model of aggregate and cumulative exposures to high production volume chemicals in air, food, water, and from residential and occupational exposures.

Project Director for the Development of Model of PBPK Parameters. This ongoing project will develop a model for generating internally consistent sets of PBPK parameters that can be used as inputs for PBPK models of inter individual variation in pharmacokinetics.

Provide on going Technical Support to ACC Glycol Ethers Panel, Methyl Bromide Panel, Children’s Health Initiative, and Solvents Panel.

Perform a dose reconstruction of PCB exposures to workers. This project required the development of a model of PCB exposure as a function of work history data, physiological measurements, and metabolic rates.

Development of LifeLine&8482; Monte Carlo software for the characterization of aggregate and cumulative exposure to pesticides. This multiyear project was funded under a cooperative agreement with EPA and USDA and funding from industry and other groups. Managed the development of the residential and tapwater portions of the software and assisted in the design of the conceptual framework for the program. This software is the only publicly available software for performing cumulative and aggregate exposure assessments for pesticides.

Development of a two-dimensional Monte Carlo model of soil exposure to PAHs from residential soils.

Development of a two-dimensional model of PCB exposure from the consumption of fish. This project resulted in the development of the first two-dimensional model of longitudinal exposures performed for an environmental contaminant. The project also successfully incorporated a quantitative model of uncertainty in the RfD into a non-carcinogenic risk assessment.

Managed a four-year dose reconstruction project for the State of Tennessee on PCB exposures at Oak Ridge, Tennessee. The project will characterize the risk to off site populations from PCBs used at the Oak Ridge Reservation over the last 50 years.

Principal in charge of CMA sponsored petition to delist ethylene glycol butyl ether as a hazardous air pollutant under the Clean Air Act.

Managing a multi-year program to evaluate risks associated with exposures to PCB-contaminated sediments in the Upper Hudson River. Directed the development of an alternative risk assessment based on new toxicological findings, site-specific exposure information, and Monte Carlo models of exposure.

Assisting with the modeling of exposure to DDT and PCBs from the consumption of fish caught in a West Coast recreational fishery (Palos Verde Shelf). This project involved the development of a Microexposure Event Model of exposure and the development of empirical models of exposure duration for angling activities. Work performed in preparation for potential litigation.

Developed and published methods for correcting sampling biases that occur during intercept surveys.

Developed a stochastic method of characterizing uncertainty and variability in indirect exposure assessments for dioxins released by incinerators for the Chemical Manufacture Association using a 2-D Monte Carlo Model.

Performed a reanalysis of the technical basis for regulatory recommendations for recreational fish consumption.

Performed a major project on dose reconstruction of the “Pliofilm” cohort exposures to benzene. This reanalysis resulted in a definitive publication on the Pliofilm cohort member’s exposure to benzene. This reanalysis has been a key part of recent occupational standard setting activities and EPA’s current program to reassess the potency of benzene.

Development of a Monte Carlo model of dose rates in populations exposed to dioxin in tapwater from multiple routes of exposure (ingestion, dermal, inhalation, and food mediated pathways).

Developed an alternative analysis of the potential for bioaccumulation of PCBs in Great Lakes fish. This analysis demonstrated that bioaccumulation rates vary by more than an order of magnitude in different Great Lakes.

Managing a project to assess the non-carcinogenic risks associated with consuming contaminated fish. EPA’s Office of Water sponsored this work.

Managing a major project with the EPA to characterize the uncertainty in the current system of safety factors used in setting RfDs. This four-year project is the first research project authorized by the EPA under the Federal Technology Transfer Act for the purposes of research in risk methodology. The results of this work have made a significant contribution to the field of non-cancer risk assessment including; techniques for quantifying the uncertainty in estimates of non-carcinogenic risk, techniques for characterizing the frequency of the occurrence of non-carcinogenic effects, and establishing a framework for using empirical data reduce the uncertainty in estimates of noncarcinogenic risk.

Organized and managed an extensive review of the immunotoxicity of PCBs. Presented a critique of the key study of PCB primate immunotoxicity to the EPA.

Managed the production of a major review and summary of the toxicology of PCBs.

Staffed the American Petroleum Institute’s Benzene Task Force. This group directed API’s program to evaluate risks from benzene in petroleum products.

Directed contracts to reevaluate carcinogenic potency of benzene, reanalyze epidemiology studies, and perform PBPK modeling of benzene and exposure assessments. Worked closely with industry toxicologists and epidemiologists to develop technical support materials on benzene potency issues.

Provided detailed technical support to API’s Office of General Council on technical aspects of Federal litigation on RCRA and Superfund actions. The support included identification of key technical issues, formulations of strategy, and review of legal documents.

Responsible for the development of formal presentations to EPA and other regulatory bodies on issues of toxicology of benzene. Met on a regular basis with Federal and State regulatory bodies.

Managed the petroleum industry’s response strategy for Land Ban and TCLP regulations under RCRA.

Organized and prepared extensive comments on proposed regulations. Assisted in the identification of potential issues for litigation.

Developed Monte Carlo model of the effect of mobility on estimates of long-term exposures to pollutants.

PUBLICATIONS AND PRESENTATIONS

P. S. Price, Conolly, R.B., Chaisson, C.F., Young, J.S., Mathis E.T., Tedder D.T. 2003. Modeling Inter-individual Variation in Physiological Factors Used in PBPK Models of Humans, Critical Reviews in Toxicology Vol. 33, (5): 469-503

M.L. Dourson , P.S. Price, J. Unrine, 2002 Health Risks from Eating Contaminated Fish Comments on Toxicology Vol. 8, Num 4-6 Pg. 399-419

P. S. Price, J. S. Young, C. F. Chaisson. 2001. Assessing Aggregate and Cumulative Pesticide Risks Using A Probabilistic Model, Annals of Occupational Hygiene, Vol 45 No. 1001, S131-S142

Wilson, N.D., P.S. Price, D.J. Paustenbach. 2001. An Event-by Event Probabilistic Methodology for Assessing the Health Risks of Persistent Chemicals in Fish: A Case Study at the Palos Verdes Shelf, Journal of Toxicology and Environmental Health, 62:595-642

Price, P., Ginevan M., Barry, T., Qualitative and Quantitative Uncertainty Analysis, Chapter 12 of Residential Exposure Assessment, 2001

Price, P.S. Chaisson C.F., Young, J.S., Christensen, C., Doyle E., Suhre, F.B., 1999. Background Document for the Session: Review of an Aggregate Exposure Assessment Tool FIFRA Scientific Advisory Panel, The LifeLine™ Project to Model Aggregate Exposures to Pesticides, Arlington, VA, September 22

Price, P.S., Keenan, R.E., Schwab B. 1999. Defining the Interindividual (Intraspecies) Uncertainty Factor. HERA, 5(5) p. 1023-1033

Carlson-Lynch, H., P.S. Price, J.C. Swartout, M.L. Dourson, and R.E. Keenan. 1999. Application of quantitative information on the uncertainty in the RfD to noncarcinogenic risk assessments. HERA 5(3) p. 527-547.

Muir, W.R., Young, J.S., Benes, C., Chaisson, C.F., Waylett, D.K., Hawley, M.E., Sandusky, C.B., Sert, Y., DeGraff, E., Price, P.S., Keenan, R.E., Rothrock, J.A., Bonnevie, N.L., McCrodden-Hamblin, J.I., A Case Study and Presentation of Relevant Issues on Aggregate Exposure, in Aggregate Exposure a Report to EPA/ ILSI Workshop, Ed. Olin, S, 1998, ILSI Press, Washington DC.

Price, P.S., P. K. Scott, N. D. Wilson, D.J. Paustenbach. 1998 An Empirical Approach for Deriving Information on Total Duration of Exposure from Information on Historical Exposures, Risk Anal. (18) 4

Swartout, J.C., P.S. Price, M.L. Dourson, H. Carlson-Lynch, and R.E. Keenan. 1998. A probabilistic framework for the reference dose, Risk Anal. (18) 3, 271-282

Price, P.S., R.E. Keenan, J.C. Swartout, C.A. Gillis, H. Carlson-Lynch, and M.L. Dourson. 1997. An approach for modeling noncancer dose responses with an emphases on uncertainty. Risk Anal. Vol 17, No. 4.

P.S. Price and Stickney, J.A. 1997. The role of statistics, policy, and management issues in the decision to adopt linear non-threshold dose response models. Comm. Toxicol., 6(2): 139-149.

Ebert, E.S., P.S. Price, and R.E. Keenan. 1996. Estimating exposures to dioxin-like compounds for subsistence anglers in North America. In: Organohalogen Compounds: Proceedings Dioxin ‘96-16th International Symposium on Chlorinated Dioxins and Related Compounds, Amsterdam, The Netherlands. 30:66-69.

Keenan, R.E., J.A. Stickney, P.S. Price, and C.A. Gillis. 1996. Implications of a recent bioassay on the cancer slope factor for PCB mixtures and resulting environmental standards. Proceedings of 1997 TAPPI Environmental Conference, Minneapolis, MN. May 4-7. Abstract.

Keenan, R.E., P.S. Price, J. McCrodden, and E.S. Ebert. 1996. Using a microexposure event analyses to model potential exposures to PCBs through ingestion of fish from the Upper Hudson River. In: Organohalogen Compounds: Proceedings Dioxin ‘96-16th International Symposium on Chlorinated Dioxins and Related Compounds, Amsterdam, The Netherlands. 30:61-65.

Keenan, R.E., N.W. Harrington, P.S. Price, and R.O. Richter. 1996. Applying a microexposure event analysis for a Superfund Site risk assessment. Superfund XVII Conference Proceedings. Washington, DC. October 15-17.

Price, P.S., R.E. Keenan. 1996. Probabilistic techniques in risk assessment: Make room in the regulatory toolbox. Risk Policy Report. 3(11): 24-26.

Price, P.S., C.L. Curry, P.E. Goodrum, M.N. Gray, J.I. McCrodden, N.W. Harrington, H. Carlson-Lynch, and R. E. Keenan. 1996. Monte Carlo modeling of time-dependent exposures using a Microexposure event approach. Risk Anal. 16(3): 339-348.

Price, P.S., S.H. Su, J.R. Harrington, and R.E. Keenan. 1996. Uncertainty and variation in indirect exposure assessments: An analysis of exposure to tetrachlorodibenzo-p-dioxin from a beef consumption pathway. Risk Anal. 16(2): 263-277.

Curry, C.L., P.S. Price, D.G. Gunster, N.L. Bonnevie, and T. B. Abel. 1995. Interlake Variation in Polychlorinated Biphenyl Bioaccumulation Factors for the Great Lakes, Water Environment Federation, Annual meeting, May

Harrington, N.W., C.L. Curry, H.J. Carlson-Lynch, and P.S. Price. 1995. The Microexposure Event Modeling Approach to Probabilistic Exposure Assessment. Air and Waste Management Annual Meeting, San Antonio. Manuscript A443. May.

Keenan, R.E., P.S. Price, and E.S. Ebert. 1995. Uncertainty and variation in indirect exposure assessments: An analysis of exposure to TCDD from a beef consumption pathway. In: Proceedings > Dioxin 95--15th International Symposium on Chlorinated Dioxins and Related Compounds, Edmonton, Alberta. August 21-25.

Ebert, E.S., P.S. Price, and R.E. Keenan. 1994. Selection of fish consumption estimates for use in the regulatory process. J. Exp. Anal. Environ. Epid. 4(3):373-394

Finley, B., D. Proctor, P. Scott, P. Price, N. Harrington, and D. Paustenbach. 1994. Recommended distributions for exposure factors frequently used in health risk assessment. Risk Anal. 14(4):533-553

Keenan, R.E., B.L. Finley, and P.S. Price. 1994. Exposure assessment: then, now, and quantum leaps in the future. Risk Anal. 14(3):225-230.

Price, P.S., R.E. Keenan, and M.C. Maritato. 1994. Strategies for Applying Innovative Risk Assessment Techniques at Superfund Sites. In: Superfund XV Conference Proceedings - Volume Two. Hazardous Materials Control Resources Institute, Rockville, MD. December.

Price, P.S., S.H. Su, and M.N. Gray. 1994. The effect of sampling bias on estimates of angler consumption rates in creel surveys. J. Exp. Anal. Environ. Epid. 4(2):355-372

Keenan, R.E., M. Henning, P. Goodrum, M. Gray, R. Sherer, and P. Price. 1993. Using A microexposure Monte Carlo risk assessment for dioxin in Maine (USA) fish to evaluate the need for fish advisories. Proceedings Dioxin ‘93 -- the Thirteenth International Symposium on Chlorinated Dioxins and Related Compounds, Vienna, Austria.

Keenan, R.E., P.S. Price, E.S. Ebert, P.E. Goodrum, M.N. Gray, and R.A. Sherer. 1993. A Monte Carlo risk assessment for dioxin in Maine fish: Using a microexposure approach to evaluate the need for fish advisories. In: Proceedings of 1993 TAPPI Environmental Conference, 907-914.

Paustenbach, D.J., R. Bass, and P. Price. 1993. Benzene toxicity and risk assessment (1972-1992): Implications for future regulations. Environ. Health Perspect.

Price, P.S. and J.M. Michaud. 1993. The new EPA guidelines for exposure assessment: Major changes at the agency. In: Proceedings of 1993 TAPPI Environmental Conference, 899-905.

Sherer, R.A. and P.S. Price. 1993. The effect of cooking processes on PCB levels in edible fish tissue. Qual. Assur: Good Practice, Reg. and Law 2(4):396-407.

Sherer, R.A., P.S. Price, and B.W. Found. 1993. The effect of cooking processes on persistent lipophilic compounds in edible fish tissue using PCB as an example. In: Proceedings of 1993 TAPPI Environmental Conference, 923-929.

Paustenbach, D.J., P.S. Price, W. Ollison, C. Blank, J. Jernigan, R. Bass, and H.D. Peterson. 1992. Reevaluation of benzene exposure for the Pliofilm (rubberworker) cohort (1936-1976). J. Toxicol. Environ. Health (36):177-231.

Price, P., J. Sample, and R. Strieter. 1991. PSEM a model of long term exposures to emissions of point sources. In: Proceedings of the 84th Annual Meeting of Air and Waste Management Association. June.

Price, P., J. Sample, and R. Strieter. 1991. Determination of less-than-lifetime exposures to point source emissions. Risk Anal. 12(3):367-382.

Price, P. 1988. Apportionment of reference doses. In: Proceedings of the Society for Risk Analysis.

Price, P. 1986. Test Rule, Diethylene Glycol Butyl Ether and Diethylene Glycol Butyl Ether Acetate, Proposed Rule, Office of Toxic Substances, 51 FR 27880.

Price, P. 1984. Acceptable levels of risk and standards. In: Proceedings of the Society for Risk Analysis.

Allman, J. and P. Price. 1980. A synopsis of perspectives on the innovative and alternative technology program. Innovative and Alternative Treatment Technology program. J. Wat. Poll. Contrl. Fed.

Sicora, L., W. Birge, L. Frank, C. Murry, and P. Price. 1978. Microbiological and chemical changes in entrenched sewage sludge. In: Proceedings of Second Annual Ann Arbor Conference on Soil and Waste Management.

PRESENTATIONS

Using Personnel Records to Model Longitudinal Exposures of Pesticide Applicators Exposed to a Soil Fumigant, P.S. Price, C.F. Chaisson, Poster Presented at Annual Meeting of the International Society for Exposure Analysis, September 2003

Assessment of Cumulative Risks from Residential Use of Organophosphorous Pesticides, P.S. Price, C.F. Chaisson, Poster Presented at Annual Meeting of the International Society for Exposure Analysis, September 2003

Modeling Inter-individual Variation in Physiological Factors Used in PBPK Models of Humans, P. S. Price, Conolly, R.B., Chaisson, C.F., Young, J.S., Mathis E.T., Tedder D.T., Poster Presented at Annual Meeting of the International Society for Exposure Analysis, September 2003

Modeling Uncertainty and Variability in Longitudinal Aggregate and Cumulative Risks Using A Nested Loop Approach, P.S. Price, C.F. Chaisson, Poster Presented at Annual Meeting of the International Society for Exposure Analysis, September 2003

Modification of Exposure and Risk Assessment Model to Profile Unique Populations: Alaska and Northern Plains Indians, P.S. Price, C.F. Chaisson, Poster Presented at Annual Meeting of the International Society for Exposure Analysis, September 2003

Modeling Residential Pesticide Exposures Using Data from Multiple Surveys, P.S. Price, C.F. Chaisson, J.S. Young. Annual Meeting of the Society for Risk Analysis, December, 2002

Using Biomarker Data to Validate Aggregate and Cumulative Exposure Models: Apples to Oranges? P.S. Price, M.S. and C. F. Chaisson, Annual Meeting of the Society for Risk Analysis, December, 2002

Answers to New Kinds of Questions Made Possible by Powerful New Risk Assessment Models, P.S. Price, M.S. and C. F. Chaisson, Annual Meeting of the Society for Risk Analysis, December, 2002

Organophosphorus Cumulative Assessment: A Comparison of Model Predictions PS Price CF Chaisson, The LifeLine Group, August 2002 Annual Meeting of the International Society for Exposure Analysis

P.S. Price, C.F. Chaisson Use of LifeLine Software for the Assessment of Cumulative Risks. Presentation to Clark University. November, 2001

P.S. Price, C.F. Chaisson, J.S. Young. Assessing Residential Exposure Using the LifeLine(TM) Model. Presented at the October 2001 Annual Meeting of the International Society for Exposure Analysis

J. H. Samuelian, B.H. Magee, W.R. Alsop, A. L. Nightingale, P. S. Price. Application of a 2-D Linear Model to Assess Uncertainty and Variability in Potential Carcinogenic Risks from Combustion Facilities: Direct and Indirect Exposure Route Presented at the October 2000 Annual Meeting of the International Society for Exposure Analysis

W. Perlberg, P.S. Price, C. F. Chaisson, M. Lytwyn, P. Bieler. The "Split-back" Methodology for Characterizing Dislodgeability of Pesticide. Presented at the October 2000 Annual Meeting of the International Society for Exposure Analysis

C. F. Chaisson, P.S. Price, J.S. Young. Age-Related Differences in Aggregate Exposure to Pesticides. Presented at the October 2000 Annual Meeting of the International Society for Exposure Analysis

P.S. Price, C. F. Chaisson, J.S. Young. Modeling Cumulative Risks from Pesticide Exposures Using Monte Carlo Modeling Analysis. Presented at the October 2000 Annual Meeting of the International Society for Exposure Analysis

C.F., Chaisson, J.S. Young, P.S. Price. 2000 Exposures from Children's Diets. Eighteenth International Neurotoxicology Conference Children's Health and the Environment Colorado Springs, CO. September

P.S. Price, R. E. Keenan, B. W. Schwab, J.I. Hamblen, A. J., Heidorn. Use of a Pharmacokinetic Model in Dose Reconstruction of Workers Exposed to PCBs. Presented at the October 2000 Annual Meeting of the International Society for Exposure Analysis

Price, P.S., Young, J.Y., Chaisson, C.F. An Approach for Modeling Constant and Variable Demographic and Exposure Information Across Individuals, Annual Meeting of the Society for Risk Analysis, December 7, 1999.

Price, P.S., Young, J.Y., Chaisson, Modeling Aggregate Exposure From Time Varying Sources. Annual Meeting of the Society for Risk Analysis, December 7, 1999.

Chaisson, C.F., Price, P.S., Young, J.Y. Age-Related Differences in Aggregate Exposures to Pesticides. Annual Meeting of the Society for Risk Analysis, December 4, 1999.

Keenan, R.E., Price, P.S., Samuelian, J.H., Hamblen, J.M. Modeling Uncertainty and Variability in Noncarcinogenic Risks from the Consumption of Fish Containing PCBs, Annual Meeting of the Society for Risk Analysis, December 7, 1998

Price, P.S. and R.E. Keenan, Characterizing the RfD/MRL/ADI in a Quantitative Framework of Uncertainty and Variability, Annual Meeting of the Society for Risk Analysis, December 7, 1998

Rothrock, J.A., P.S. Price, R.E. Keenan, E.S. Ebert, C.F. Chaisson, W.R. Muir, The Application of Microexposure Event Modeling to the Evaluation of Water Related Exposures, Annual Meeting of the Society for Risk Analysis, December 7, 1998

Price, P.S., Keenan, R.E., Schwab B. 1998. Defining the Interindividual (Intraspecies) Uncertainty Factor. Third Annual Workshop on Evaluation of Default Safety Factors in Health Risk Assessment, November 11, 1998

Price, P.S., R.E. Keenan, and S.J. Pauwels. 1998. Using an Integrated Microexposure Event and Toxicokinetic Model to Evaluate the Impact of Dioxin Intakes from the Consumption of Maine Freshwater Fish on Angler Bodyburdens. 25th Annual Aquatic Toxicity Workshop. Quebec, Canada, October 21

Price, P.S. 1998. Modeling Exposure and Risk, ELI-ABA, Workshop on Risk Assessment Risk Management in Environmental Law, Washington DC, October 9-10

Price, P.S. 1998. Characterizing Risks from Doses above the ADI, ILSI-Europe Workshop on the Significance of Excursions of Intake above the ADI, Milan, Italy, April 21-23

Gillis, C.A., P.S. Price, and J. I. Mcrodden-Hamblen. 1998. Use of a probabilistic analysis to characterize the uncertainty in the PCB threshold dose. Toxicological Sciences (Suppl.) 42(1-S):45. Abstract 224.

Price, P.S. and R.E. Keenan. 1998. Advances in non-carcinogenic risk assessment. Toxicology Round Table of the American Crop Protection Association. Seattle, WA. February 28.

Price, P.S., and R.E. Keenan. 1998. Microexposure event modeling an approach to modeling time-varying exposures. New England Chapter - Society for Risk Analysis. Boston, MA. March 11.

Price, P.S., R.E. Keenan, J.A. Rothrock, C.F. Chaisson, D.K. Waylett, M.E. Hawley, C.B. Sandusky, R. Sert, E. DeGraff, W.R. Muir, and J.S. Young. 1998. A case study and presentation of relevant issues on aggregate exposure. ILSI Aggregate Exposure Workshop Program. Washington, DC. February 9-10.

Stickney, J.A., C.A. Gillis, P.S. Price, and R.E. Keenan. 1998 Application of uncertainty factors (UFs) for developmental reference doses (RfDs) for Aroclor 1254. Toxicological Sciences (Suppl.) 42(1-S):45. Abstract 1113.

Carlson-Lynch H., R.E. Keenan, J.C. Swartout, and P.S. Price, M.L. Dourson. 1997. Effect of uncertainty distributions for RfDs on noncancer risk estimates. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 208. Abstract 1055.

Chaisson, Chris, D.K. Waglett, P.S. Price. J. Rothrock. 1997. Probabilistic Methods: Using New Data Sources and Examining the Answers: Implications for Multiple Chemical Exposure Assessment. Society for Risk Analysis/International Society of Exposure Assessment Conference. Washington, D.C. December 8.

Gillis C.A., R.E. Keenan, H.L. Carlson-Lynch, and P.S. Price. 1997. Characterization of the interindividual (UF_H) factor: Alternative models and approaches. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 207. Abstract 1053.

Harvey T., R.E. Keenan, J.C. Swartout, H.L. Carlson-Lynch, C.A. Gillis, and P.S. Price. 1997. Application of probabilistic methods to noncarcinogenic risk assessment: A case study of hexachloroethane and paraquat. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 208. Abstract 1059.

Keenan, R.E., J.D. Avantaggio, and P.S. Price. 1997. Using a combined Microexposure Event and Toxicokinetic Model to evaluate the need for fish advisories based on a body burden dosimetric. In: Society for Risk Analysis Proceedings, Annual Meeting and Exposition. Abstract.

Keenan, R.E., J.D. Avantaggio, and P.S. Price. 1997. Should Maine’s rivers have fish advisories for dioxin? Using an integrated Microexposure Event and Toxicokinetic Model to evaluate this question. In: SETAC North Atlantic Chapter Annual Meetings Proceedings. Abstract 1.

Keenan, R.E., J.A. Rothrock, and P.S. Price. 1997. Should Maine’s rivers have fish advisories for dioxin? Society for Risk Analysis. Washington, DC. December 10.

Keenan, R.E., J.A. Stickney, B. Mayes, C.A. Gillis, P.S. Price, and S.B. Hamilton. 1997. Implications of a recent feeding study on the cancer slope factor for PCB mixtures. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 157. Abstract 801.

Kerger, B.D., P.S. Price, 1997. Use of Probabilistic Models to Illustrate Reasonable Scientific Certainty of Dose and Risk Estimates in the Courtroom. Society for Risk Analysis, Washington, D.C. December 8.

Chaisson, C.F., D.K. Waglett, P.S. Price, and J.A. Rothrock. 1997. Probabilistic methods: Using New Data Sources and Examining the Answers: Implication for Multiple Chemical Exposure Assessment. Society for Risk Analysis. Washington, DC. December 8.

Price, P.S. 1997. Better characterization of inter-personal variation using Microexposure event modeling. Society for Risk Analysis. Washington, DC. December 7.

Price, P.S., P.K. Scott, N.D. Wilson, and D.J. Paustenbach. 1997. An empirical approach for deriving information on total duration of exposure from information on historical exposure from surveys. Society for Risk Analysis. Washington, DC. December 10

Price, P.S., R.E. Keenan, H. Carlson-Lynch, and C. Gillis. 1997. Defining the interindividual uncertainty factor (UHF): Implications for non-cancer dose response modeling. Society for Risk, Washington, DC. December 8.

Price P.S., R.E. Keenan, J.C. Swartout, M.L. Dourson, and H.L. Carlson-Lynch. 1997. An approach for characterizing dose-response rates for noncarcinogens. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 208. Abstract 1056.

Schmidt C.W., C.A. Gillis, R.E. Keenan, and P.S. Price. 1997. Characterizing inter-chemical variation in the interspecies uncertainty factor (UF_A). Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 208. Abstract 1057.

Swartout J.C., R.E. Keenan, J.A. Stickney, C.A. Gillis, H.L. Carlson-Lynch, M.L. Dourson, T. Harvey, and P.S. Price. 1997. A probabilistic framework for the reference dose. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 208. Abstract 1054.

Avantaggio J.D., P.S. Price, S. Hays, M. Gargas. 1997. Use of microexposure event modeling to estimate polychlorinated biphenyl (PCB) concentrations in the blood of anglers who consume contaminated fish. 1997. Fundamental and Applied Toxicology (Supplement) 36(1 Part 2): 283 Abstract 1441.

Avantaggio, J.D., P.S. Price, and R.E. Keenan. 1997. Use of Microexposure Event Modeling to estimate tetrachloredibenzo-p-dioxin toxic equivalent concentrations in the blood of Maine anglers who consume freshwater fish. In: SETAC North Atlantic Chapter Annual Meeting Proceedings. Abstract 18.

Keenan, R.E., P.S. Price. 1997. Characterizing the Uncertainty in the Reference Dose (RfD). New England Chapter of The Society for Risk Analysis. Cambridge, MA. February 26.

Keenan, R.E., and P.S. Price. 1997. FQPA aggregate exposure and common mode of action assessments: New approaches. American Bar Association Section of Natural Resources, Energy, and Environmental Law. Environmental quality Committee. Washington, DC. September 9.

Widner, T.E., P.S. Price, J. McCrodden-Hamblen, and N. Bonnevie. 1997. Historical doses and health risks from PCBs in the environment near Oak Ridge, Tennessee. Society for Risk Analysis/International Society of Exposure Assessment Conference. Washington, DC. December 8.

Wilson, N.D., N.M. Shear, D.J. Paustenbach, and P.S. Price. 1997 The effects of cooking practices on levels of DDT and PCB compounds in the edible tissue of fish. Society for Risk Analysis. Washington, D.C. December 10

Gillis, C.A. and P. Price. 1996. Comparison of noncarcinogenic effects and PCB body burdens in rhesus monkeys and humans: Implications for risk assessment. The Toxicologist (Supplement) 30(1):146.

Keenan, R.E., Ebert, E.S., and P.S. Price. 1996. Estimating exposures of subsistence anglers. Society for Risk Analysis/International Society of Exposure Assessment Conference. December.

Keenan, R.E., N.W. Harrington, P.S. Price, and R.O. Richter. 1996. A comparison of potential risks using default point estimates, Monte Carlo modeling, and Microexposure event analysis for evaluating impacted groundwater near the Stringfellow Superfund Site. Superfund XVII Conference Proceedings. Washington, DC. October 15-17.

McCrodden, J.I., P.S. Price, N.L. Bonnevie, J.D. Avantaggio, and E.S. Ebert. 1996. Characterizing the uncertainty in estimates of PCB risk from the Clinch and Tennessee Rivers. In: Society for Risk Analysis and International Society of Exposure Analysis (SRA). New Orleans. December 8-12.

Price, P.S., R.E. Keenan. 1996. Characterization of the interindividual (UF_H) Factor: Alternative Models and approaches. National Health and Environmental Effects Research Laboratory. September 24-27.

Price, P.S. 1996. Management of chemicals noncarcinogenic effects using a mechanistic approaches. Society for Risk Analysis/International Society of Exposure Assessment Conference. New Orleans. December 8-12.

Price, P.S., and R.E. Keenan. 1996. An approach for extrapolating dose rate information from animals to humans. Society for Risk Analysis/International Society of Exposure Assessment Conference, New Orleans. December 8-12.

Price, P.S., R.E. Keenan, J. Avantaggio, and C. Curry. 1996. Use of stochastic models to characterize variation in lifetime, chronic, and subchronic dose rates in an exposed population with temporal and age-related variability. The Toxicologist (Supplement) 30(1):115.

Richter, R.O., N. Harrington, C. Curry, S. El-Sururi, P. Price, and B. Kerger. 1996. Comparison of risk estimates derived from standardized point estimate, traditional Monte Carlo analysis, and microexposure analysis for the domestic use of trichloroethylene impacted groundwater. The Toxicologist (Supplement) 30(1):115.

Stickney, J., P. Price, and R. Keenan. 1996. Interindividual variation under the current system of uncertainty factors. The Toxicologist (Supplement) 30(1):148.

Price, P.S. 1996. Application of Monte Carlo to Toxicological Uncertainty in Quantitative Uncertainty Analysis in risk Assessment: Monte Carlo Techniques. Continuing Education Course PM #12, Society for Toxicology, 35th Annual Meeting. March

Harman, C., C.S. Crockett, C.P. D'Alleinne, P.S. Price, and K. Schild. 1995. Use of Monte Carlo analysis to evaluate multimedia ecological risks and impacts. In: Society for Risk Analysis and the Japan Section of SRA, Annual Meeting and Exposition, Sheraton Waikiki, HI.

Price, P.S. 1995. Human health risk assessment: Report from the frontlines. Presented at What You Need to Know About Risk Assessment and Why, Capitol Hill Club, Washington, D.C. March 1.

Price, P.S., R.E. Keenan, J.C. Swartout, C.A. Gillis, and M.C. Dourson. 1995. A Monte Carlo based approach for modeling noncarcinogenic dose response rates. In: Society For Risk Analysis and the Japan Section of SRA, Annual Meeting and Exposition, Sheraton Waikiki, HI.

Swartout, J., L. Knauf-Teuschler, P.S. Price, C.A. Gillis, and R.E. Keenan. 1995. Application of a Monte Carlo based approach for modeling non-carcinogenic dose response. In: Society for Risk Analysis and the Japan Section of SRA, Annual Meeting and Exposition Sheraton Waikiki, HI.

Su, S.H., P.S. Price, J.R. Harrington, T.B. Abel, and C.L. Curry. 1994. Assessing uncertainty and variability of indirect exposure to dioxin emission from hazardous waste incinerator. Annual Meeting of the Society for Risk Analysis. December.

Keenan, R.E., M. Dourson, P. S. Price, J. Swartout, and Steve Su. 1994. EPA - McLaren/Hart-ChemRisk Joint Project to Develop a Stochastic Approach for Assessing Non-carcinogenic Risk - A Status Report. Annual meeting of the Society for Risk Analysis. December.

Price, P.S., R. E. Keenan, and S. Su. 1994. Accounting for Inter-individual Variation in the Current System of Safety Factors. Annual meeting of the Society for Risk Analysis. December.

Keenan, R.E. and P.S. Price. 1994. Development of a Monte Carlo model of uncertainty and variability in reference doses. Poster presentation describing a Cooperative Research and Development Agreement (CRADA) project between McLaren/Hart and the U.S. Environmental Protection Agency. Presented at the Annual Meeting of the Society of Toxicology, Dallas, TX. March 14.

Price, P.S. 1994. Identifying distributions for commonly used exposure factors. In: Workshop on the Application of Monte Carlo Modeling to Exposure Assessment, Annual meeting of the Society for Risk Analysis. December.

Price, P.S. 1994. Application of Monte Carlo modeling to Exposure Scenarios. In: Workshop on the Application of Monte Carlo modeling to Exposure Analysis, Annual Meeting of the Society for Risk Analysis. December.

Ebert, E.S., P.S. Price, and R.E. Keenan. 1994. Selection of fish consumption estimates for use in the regulatory process. International Society for Environmental Epidemiology/International Society for Exposure Assessment Joint Conference, Research Triangle Park. September 18-21.

Price, P.S. 1993. Monte Carlo modeling of exposure: Case Example in Workshop on the application of Monte Carlo modeling to exposure and risk assessment. Annual meeting of the Society for Risk Analysis. December.

Price, P.S. 1993. Application of Monte Carlo modeling to dose response estimates in Workshop on the Application of Monte Carlo modeling to Exposure and Risk Analysis. Annual meeting of the Society for Risk Analysis. December.

Price, P.S. 1993. Incorporating human-activity pattern and population mobility data into residential exposure assessment in Reference House Workshop II: Residential exposure assessment for the 1990s. Annual meeting of the Society for Risk Analysis. December.

Price, P.S., M.N. Gray, P.E. Goodrum, and R.E. Keenan. 1993. Exposure assessment scenario-based models. In: ATSDR International Congress on the Health Effects of Hazardous Waste, Atlanta, GA. May 3.

Price, P.S., D. Gunster, J. Knight, and M. Gray. 1993. The role of predator (mink) feeding ranges in establishing soil/sediment cleanup standards. In: ASTM Environmental Toxicology and Risk Assessment Symposium, Atlanta, GA. April 28.

Price, P.S. and J.M. Michaud. 1993. The new EPA guidelines for exposure assessment: Major changes at the agency. In: Proceedings of 1993 TAPPI Environmental Conference Boston, MA. March 31.

Paustenbach, D.J. and P.S. Price. 1992. Historical reconstruction of benzene exposures for an occupational cohort of rubber workers. In: Annual meeting of the Society for Risk Analysis, December.

Price, P.S., P. Goodrum, and M.N. Gray. 1992. The role of short and long term variation in Monte Carlo Modeling. In: Annual Meeting of the Society for Risk Analysis, December.

Price, P.S. 1992. Recent revisions in EPA guidelines for exposure and risk assessment. In: The Environment in the 90s: New Approaches to Regulations, 17th Annual Industry/Environment Conference, Saratoga Springs, NY. October 22.

Price, P.S. 1992. Residential mobility case study in workshop on residential exposure. Annual Meeting of the Society for Risk Analysis. December.

Price, P.S. 1991. Lecture on Occupational Risks Associated with Benzene Exposure. Harvard School of Public Health. September.

Price, P.S., J. Sample, and R, Strieter. 1990. A methodology for estimating the maximum exposed individual. In: Annual Meeting of the Society for Risk Analysis. November.

Price, P.S. 1990. Lecture on Occupational Risks Associated with Benzene Exposure. Harvard School of Public Health. September.

Price, P.S. 1987. Apportionment of reference doses. In: Annual meeting of the Society of Risk Analysis. October.

Price, P.S. 1986. The role of temperature on drinking water intake. In: Annual Meeting of the Society of Risk Analysis. September.

Price, P.S. and J. Lefler. 1985. Risk model for aquatic toxicity of cationic polymers. Presentation Society of Environmental Toxicity and Chemistry. November.

Price, P.S. 1984. The role of acceptable levels of risk in setting chemical standards. In: Annual meeting of the Society for Risk Analysis. October.

Editorial Boards

Risk Analysis: An International Journal (1996-2002)
Regulatory Toxicology and Pharmacology: (1998- 2001)

Awards and Honors

Society of Toxicology Award for the Outstanding Paper in Risk Assessment (1997).
Society of Toxicology Awards for the Outstanding Presentation in Risk Assessment (1996)
(Two awards)
McLaren/Hart Award of Excellence, 1995
API Meritorious Bonus Award. For efforts on development of response to proposed waste regulations under Clean Air Act, 1990
EPA Bronze Medal. For development of fluoride drinking water standards, 1987
EPA Bronze Medal. For meeting court-ordered deadline for publication of regulations under Section 4 of Toxic Substances Control Act, 1982

Professional Affiliations

Society for Risk Analysis (Charter member)
Treasurer, 1994-1998
Chair of Exposure Analysis Special Interest Group (1990-1993),
Conference committee member for 1994, 1995, and 1998 Annual Conferences
Management committee for the SRA/EPA/Industry Residential Exposure Handbook
Peer Review committee for the SRA/EPA/Harvard Monte Carlo project

International Society for Exposure Analysis (Charter member)
Liaison with the Society for Risk Analysis (1991-2002)
Councilor (2000-2003)

Society for Toxicology (1996)

Federal, State, and Industry Workshops and Peer Review Panels

EPA-ACE External Peer Review of the HARS Risk Assessment. This two-year appointment required a review of the human and ecological risks associated with the placement of remediation materials at the Historic Area Remediation Site (HARS) in New York Harbor. (2002-2003)

EPA-ACC Technical Workshop on the Voluntary Children’s Chemical Evaluation Program (VCCEP) -Served on expert panel and made a presentation on relevance of exposure models to the Assessment of Children’s Exposure, December, 2001

EPA External Peer Review of “Exposure Analysis for Dioxins, Dibenzofurans, and coplanar Polychlorinated Biphenyls in Sewage Sludge, December 2001

TERA Workshop Risk Characterization for Non-Lethal Weapons: Workshop to Develop Framework (2001-2)

EPA External Peer Review of RAGS Guidance on the Use of Probabilistic Models (2000) Served as chair of human health subcommittee of the external peer review panel for proposed guidance on the use of Monte Carlo modeling in the assessment of exposures at Superfund sites.

Risk Forum Colloquium on Approaches to Quantifying Health Risks for Threshold or Non-Linear Effects at Low Doses (2000).

Exposure Assessment Technical Implementation Panel of the Chemical Manufacturers Association Research Initiative (1998-2000).

EPA workshop on Future NHEXAS related research, July 20, 1999.

EPA workshops for the revision of the Exposure Factors Handbook (1994,1996) Supervised the development of detailed comments on interim drafts. Invited participant at all external review workshops.

Development of guidance on the use of Monte Carlo (1994-1997). Served on three review panels for EPA guidance and served as external reviewer for final drafts of EPA guidance document “Policy for Use of Probabilistic Analysis in Risk Assessment”, May 15, 1997.

External peer reviewer of PCB carcinogenic potency assessment. Member of external peer review for revision of EPA guidance document for PCB carcinogenicity.

External peer reviewer of site-specific mercury reference dose. Member of ITER peer review panel for establishing a safe intake level for mercury from the consumption of fish (1997).

Member of State of California Risk Assessment Advisory Committee (1996-7). Exposure assessment subcommittee. Reviewed and prepared written comments on all interim and final reports.

External Peer Reviews Performed for EPA
1998 Review of proposals for intramural research for NCEA.
1998 Review and beta test of residential exposure software.
1999 Review of studies on interindividual variation in exposure parameters.

Dr. Michael A. Jayjock

Doctor of Philosophy June 1984 Drexel University, Philadelphia, Pennsylvania

Master of Science, June 1981, Drexel University, Philadelphia Pennsylvania

Bachelor of Science, June 1968, The Pennsylvania State University, State College, Pa.

Certification:Certified in the Comprehensive Practice of Industrial Hygiene by the American Board of Industrial Hygiene

Employment History

2003 Senior Analyst, LINEA Inc. Senior Analyst, The LifeLine Group, Inc.

1995-2002 Senior Research and EHS Fellow and Manager, Risk Assessment , Rohm and Haas Company Toxicology Department

1991-1995 Technical Fellow and Manager, Risk Assessment , Rohm and Haas Company Toxicology Department

1990-1991 Technical Fellow, Rohm and Haas Company Corporate Product Integrity Department

1984-1990, Senior Product Safety Engineer, Rohm and Haas Company, Corporate Product Integrity Department

1983-1984 Scientist, Rohm and Haas Company, Plastics Intermediate Technical Service

1979-1982 Group Leader, Rohm and Haas Company , Physical Measurement Group, Plastics Technical Service

1969-1979 Engineer, Rohm and Haas Company, Plastics Technical Service

Dr. Michael Jayjock is a Senior Analyst with LINEA Inc. with expertise in consumer and occupational exposure and risk characterization. Dr. Jayjock recently left the Rohm and Haas Company where he was a Senior Research and Environmental Health and Safety Fellow and Manager for Risk Assessment. At Rohm and Haas he was responsible for the determination of human health risk from exposure to Rohm and Haas products, reactants, and intermediates. Dr. Jayjock was a member of the National Research Council’s Subcommittee on Flame Retardant Chemicals, and, in this capacity, he participated in the review of decabromodiphenyl oxide (aka, decabromodiphenyl ether).

Dr. Jayjock’s professional activities include membership in numerous scientific societies and participation on many professional review boards. He has been a member of EPA’s Science Advisory Board, Integrated Human Exposure Committee; and is a member of and serves on several committees of the National Research Council - National Academy of Sciences. In addition, he is a Member of the Peer Review Panel for the science program at the National Exposure Assessment Laboratory of the US Environmental Protection Agency. He has authored or coauthored numerous publications and given invited presentations on risk assessment, occupational exposure, industrial hygiene, and modeling.

Dr. Jayjock also serves as a Guest Lecturer for universities and professional organizations. He is a Guest Lecturer at the University of Pennsylvania Medical School, Residency Program for Occupational Medicine; and he is also an Instructor for a Professional Development Course on risk assessment for the American Industrial Hygiene Conference and Exposition. Previously, he served as Course Director and Instructor for Risk Assessment and Intermediate Exposure Modeling at the University of North Carolina Education Research Center, Summer Institute.

PUBLICATIONS AND PRESENTATIONS

Jayjock, M.A.: Modeling Inhalation Exposure, Chapter 8 in The Occupational Environment - Its Evaluation and Control, in press, American Industrial Hygiene Association, Fairfax, VA (2003).

Jayjock, M.A. and P.G. Lewis: Implications of Hormesis for Industrial Hygiene, Human & Environmental Toxicology 21: 385-389 (2002).

M. Nicas and M.A. Jayjock: Uncertainty in Exposure Estimates Made by Modeling versus Monitoring, Am. Ind. Hyg. Assoc. J. 63 : 275-283 (2002).

M.A. Jayjock, P.G. Lewis and J.R. Lynch: Quantitative Level of Protection Offered to Workers by ACGIH Threshold Limit Values (TLV? ) Occupational Exposure Limits, Am. Ind. Hyg. Assoc. J. 62 : 4-11 (2001).

Nelson, T.J, M.A. Jayjock and C.E. Colton: How Protective Are Respirator Assigned Protection Factors? : An Uncertainty Analysis, Am. Ind. Hyg. Assoc. J. 61: 388-393 (2000).

Jayjock, M.A.: Chapters 1 and 6 in Mathematical Models for Estimating Occupational Exposure to Chemicals, edited by C.B. Keil, American Industrial Hygiene Association, Fairfax, VA (2000).

Jayjock, M.A., J.R. Lynch and D.I. Nelson, Risk Assessment Principles for the Industrial Hygienist, American Industrial Hygiene Press, 2700 Prosperity Avenue, Fairfax, VA, May, 2000.

Jayjock, M.A: Risk Assessment of Contact Allergens, American Journal of Contact Dermatitis, 9 (3): 155-161 (1998).

Jayjock, M.A. and J.E. Franke: A Strategy for Occupational Exposure Assessment, Appendix I, Estimating inhalation exposure with physical-chemical models, American Industrial Hygiene Association, Fairfax, VA (1998).

Jayjock, M.A.: Modeling Inhalation Exposure, chapter 16 in The Occupational Environment - Its Evaluation and Control, edited by S.R. DiNardi, American Industrial Hygiene Association, Fairfax, VA (1997).

M.A. Jayjock, K.H. Reinert, H.E. Scribner, et al: Total Quality Management of the Risk Assessment Process, Am. Ind. Hyg. Assoc. J. 58 (11): 814-819 (1997).

Shade, W.D. and M.A. Jayjock:. "Monte Carlo Uncertainty Analysis of a Diffusion Model for the Assessment of Halogen Exposure during Dosing of Brominators, " Am. Ind. Hyg. Assoc. J. 58 (6): 418-424 (1997).

Jayjock, M.A.: Uncertainty Analysis in the Evaluation of Exposure, Am. Ind. Hyg. Assoc. J. 58 (5): 380-382 (1997).

Weiler, E.D., M.A. Jayjock, and H.C. Levy: Product Safety, Risk Assessment, and Responsible Care in the Biocide Chemical Industry, Reg Tox. Pharm. 24, 1-5 (1996).

Jayjock, M.A. G.A. Hazelton, P.G. Lewis and M.F. Wooder: Formulation Effect on the Dermal Bioavailability of Isothiazolone Biocide, Fd. Chem. Toxic. Vol 34, No. 3, ppp 277-282 (1996).

Jayjock M. A , Deepak R. Doshi, Edwin H. Nungesser, and William D. Shade: Development and Evaluation of a Source/Sink Model of Indoor Air Concentrations from Isothiazolone Treated Wood Used Indoors, Am. Ind. Hyg. Assoc. J. 56 (6): 546-557 (1995).

Jayjock, M.A. and N. C. Hawkins: Exposure Database Improvements for Indoor Air Model Validation, Appl. Occup. Environ. Hygiene 10 (4): 379-382, April (1995).

Lewis, P.G, and M.A. Jayjock, Risk Assessment Modeling: Allergic Contact Dermatitis Application, American Journal of Contact Dermatitis, 5(3): 143-149, September (1994).

Jayjock, M.A.: Back Pressure Modeling of Indoor Air Concentration From Volatilizing Sources, Am. Ind. Hyg. Assoc. J. 55 (3): 230-235 (1994).

Committee to Review Risk Management in the DOE’s Environmental Remediation Program: Building Consensus Through Risk Assessment and Management of the Department of Energy’s Environmental Remediation Program National Research Council, National Academy Press, Washington, D.C. (1994).

Jayjock, M.A. and N.C Hawkins: A Proposal for Improving the Role of Exposure Modeling in Risk Assessment, Am. Ind. Hyg. J. 54(12):733-741 (1993).

Weiler, E.D., M.A. Jayjock, and D.E. Greenley: Quality Requirements for Biocides in the 1990s, Quality Assurance: Good Practice, Regulation, and Law., 2(3): 244-250 (1993).

Weiler, E.D., M.A. Jayjock, and H.E. Scribner: A Quality Process for Chemical Product Risk Assessment, Quality Assurance: Good Practice, Regulation, and Law., 1(4): 295-301 (1992).

Jayjock, M.A. and P.G.: Lewis: Low-Applied-Dose Extrapolation of Induction and Elicitation of Contact Allergy in the Evaluation and Management of Sensitization Risk from Kathon CG Isothiazolone in Products, American Journal of Contact Dermatitis, 3(2): 86-91 (1992).

Committee on Advances in Assessing Human Exposure to Airborne Pollutants: Human Exposure Assessment for Airborne Pollutants, National Research Council Board of Environmental Studies and Toxicology, National Academy of Science, National Academy Press, Washington, D.C. (1991).

Rosenthal I., M.A. Jayjock, R.L. Keener, and J.E. Plamondon: Regulating the Introduction of New Chemicals Under Section 5 of TSCA - Improving the Efficiency of the Process and Reducing Potential Injury in the Workplace Through the Use of Operational MSDS and Exposure Limits, Quality Assurance: Good Practice, Regulation, and Law., 1(1):10-30, (1991).

Hawkins, N.C., M.A. Jayjock, and J.R. Lynch: A Rationale and Framework for Establishing the Quality Of Human Exposure Assessments, 53(1):34-41, Am. Ind. Hyg. J. (1991).

Jayjock, MA, and J.N. Moss, Assessing the Risk of Toxicity, Manufacturing Chemist 60: (9) 37-38 September 1989

Jayjock, M.A. and S.C. Gad: Hazard and Risk Assessment, Chapter 15 in Product Safety Evaluation Handbook, edited by S.C. Gad, Marcel Dekker, New York (1988).

Jayjock, M.A. and K.A. Hulik: Workroom Air Monitoring of Isothiazolone Biocide from Metal Working Fluids, J. Am. Soc. Lubr. Eng. 44 (3): 262-264 (1988).

Jayjock, M.A.: Assessment of Inhalation Exposure Potential from Vapors in the Workplace, Am. Ind. Hyg. Assoc. J. 49(8): 380-385, (1988).

Jayjock, M.A. and L. Levin: Health Hazards in a Small Automotive Body Repair Shop, Ann. Occup. Hyg. 28(1): 19-29 (1984).

TECHNICAL PRESENTATIONS

“Biomarker Research as Viewed by an Interested and Hungry Risk Assessor”, presented at Applying Biomarkers to Occupational Heath Practice - Exposure Assessment Methods Workshops, NIOSH/NORA/CDC, LaFonda on the Plaza, Santa Fe, NM, March 24, 2003.

“Implications of Hormesis for Industrial Hygiene”, presented at Non-Linear Dose-Response Relationships in Biology, Toxicology and Medicine, University of Massachusetts, Amherst, MA, June 13, 2002.

“What HPV Could Mean to Industrial Hygiene Risk Assessment”, presented at the American Industrial Hygiene Conference and Expo, AIHA Forum 211, San Diego, CA, June 3, 2002.

“Uncertainty Analysis in the Risk Assessment of Contact Allergens”, presented at Contact Dermatitis: State-of-the-Art Issues, sponsored by The American Contact Dermatitis Society, the Penn State Continuing Education Department and the Rohm and Haas Company, Hershey PA, July 13 (2001).

“Research in Human Health Exposure Assessment”, AIHA Forum 307, American Industrial Hygiene Conference, New Orleans, LA, June 4, 2001.

“Quantitative Level of Protection Offered to Workers by ACGIH Threshold Limit Values (TLV Occupational Exposure Limits", AIHA Technical Session 123 Presentation, American Industrial Hygiene Conference, Orlando, Florida, May 24, 2000.

“MODELS: An Indispensable Element of the Science of Exposure Assessment”, Mickey Leland Center Workshop, The Role of Human Personal Exposure Assessment in Determining Health Impacts of Urban Air Toxics, M.D. Anderson Cancer Center, Houston, TX, March 7, 2000

“An Exposure Assessment Modeler’s Biased and Hungry View of Exposure Databases”, ACGIH International Symposium on Occupational Exposure Databases and Their Application for the Next Millennium, The Forum Hotel, London, UK, November 3, 1999

“Relationship Between Ambient Levels and Personal Exposure”, Air Toxics Monitoring Workshop to Support EPA's Integrated Urban Air Toxics Strategy. Research Triangle Park, NC, June 2, 1999.

"The Human Health Risk Assessment Process", invited speaker for the American Industrial Hygiene Association New Jersey Section Meeting, Nassau Inn, Princeton, NJ, January 21, 1999.

"Product Safety, Risk Assessment and Responsible Care, presented at the ACGIH Professional Conference on Industrial Hygiene (PCIH), Baltimore, Md., September 29, 1997.

"Risk Assessment Of Contact: Allergy", presented at Contact Dermatitis: State-of-the-Art Issues, sponsored by The American Contact Dermatitis Society, the Penn State Continuing Education Department and the Rohm and Haas Company, Hershey PA, July 12 (1997).

"Risk Assessment - The Uncertainty Factor", AIHA Roundtable Presentation, American Industrial Hygiene Conference, Dallas, Texas, May 22, 1997.

"Risk Assessment of Contact Allergens", Jadassohn Centenary Conference on Contact Allergy, London, UK, October 12, 1996.

"The Risk Assessment Process. Product Stewardship - Case History", American Chemical Society -Council for Chemical Research, Conference on Risk Assessment in Education, Hotel Du Pont, Wilmington, DE, September 28, 1996

"Uncertainty as the Bane of the Risk Assessment Process", Testimony before the President’s Commission on Risk Assessment and Risk Management, Washington, D.C., September 14, 1995

Nungesser, E.H, M.A. Jayjock, D.R. Doshi, W.D. Shade and T.M. Williams " A laboratory microcosm model to determine fate of components from metal working fluid systems", , Poster presentation at "The Industrial Metalworking Environment: Assessment and Control Symposium", Dearborne Michigan, November 13-16, 1995.

"Methodologies Used in the Assessment of Inhalation Exposure Potential of Rohm and Haas Products", Rohm and Haas Research Division Tech Fair, Spring House, PA, October 4-6, 1994.

"Case Study III: Indoor Air Model Development for Biocide Offgassing in the Home", International Society of Exposure Assessment Workshop Presentation, ISEA Conference, Sheraton Hotel, Research Triangle Park, NC, September 18, 1994.

"Risk Assessment and the Industrial Hygienist", invited speaker, Delaware Valley Chapter of the American Industrial Hygiene Association, Fall Diner Meeting, Guest Quarters Hotel, Plymouth Meeting, PA, September 13, 1994.

"Four Critical Components of Risk Assessment and the Need for Toxicology and Exposure Model Development", AIHA Forum 5, American Industrial Hygiene Conference, Anaheim, California, May 25, 1994.

"Exposure Models - Overview and Current State-of-the-Science",

AIHA Roundtable Presentation, American Industrial Hygiene Conference, Anaheim, California, May 21, 1994.

"An Industrial Perspective on Risk Assessment and Research Needs", invited conference presentation for CERCLA, RCRA,CWA, ETC.... How Clean is Clean?, Sponsored by the National Environmental Policy Institute and Environment Week, The Mayflower Hotel, Washington, D.C., May 10, 1994.

NAS-National Research Council, Workshop to Review Risk Management in DOE’s Environmental Remediation Program, Panel Discussant, National Academy of Sciences Building, Washington, D.C., November 3, 1993.

Jayjock M. A , Deepak R. Doshi, Edwin H. Nungesser, and William D. Shade: Development and Evaluation of a Source/Sink Model of Indoor Air Concentrations from Isothiazolone Treated Wood Used Indoors, Paper 165, AIHA Conference and Exposition, Anaheim, California, May 1994.

Lewis, P.G. and M.A. Jayjock: RISK ASSESSMENT MODELING: ALLERGIC CONTACT DERMATITIS APPLICATION, presented at Contact Dermatitis: State-of-the-Art Issues, sponsored by The American Contact Dermatitis Society, the Penn State Continuing Education Department and the Rohm and Haas Company, Hershey PA, October 25 and 26 (1991).

Jayjock, M.A. and N.C. Hawkins: MODEL DEVELOPMENT AND VALIDATION ARE THE KEYS TO SCIENTIFIC RISK ASSESSMENTS OF INHALATION AND DERMAL EXPOSURES, Joint EPA/ACS Symposium on Risk Assessment, 102nd ACS National Meeting, NYC, August 25-30 (1991).

McGuigan, F.P., J.E. Franke, N.C. Hawkins, M.A. Jayjock, M. Madjdinasab, J.L. Unmack: OCCUPATIONAL EXPOSURE MODELING: AN EMERGING AREA FOR INDUSTRIAL HYGIENISTS. Paper 269, American Industrial Hygiene Association Conference and Exposition, Salt Lake City, May (1991).

Jayjock, M.A.: OCCUPATIONAL EXPOSURE AND RISK ASSESSMENT IN THE 1990s, American Industrial Hygiene Association Symposium on Occupational Health in the 90s, Cincinnati, OH, November (1990).

Jayjock, M.A.: QUANTITATIVE RISK ASSESSMENT MODELING OF DERMAL SENSITIZATION FROM KATHON CGtm BIOCIDE IN COSMETICS, Dermal Clinical Evaluation Society, Elizabeth, NJ., June (1990).

Jayjock, M.A.: BACK PRESSURE MODELING OF INDOOR AIR FROM EVAPORATING SOURCES, American Industrial Hygiene Associate Conference, Orlando, FL, May (1990).

Jayjock, M.A.: MODELING OF INHALATION EXPOSURE POTENTIAL IN THE WORKPLACE, American Occupational Health Conference of the American Occupational Medical Association, Philadelphia, PA., May (1987).

Jayjock, M.A. and L. Levin: ASSESSMENT OF INHALATION EXPOSURE AND HEALTH RISK FROM ORGANIC VAPORS, American Industrial Hygiene Association Conference, Dallas, TX., May (1986).

Jayjock, M.A. and L. Levin: SAMPLING BIAS FROM AEROSOL ELECTROSTATIC CHARGE AND PARTICLE SIZE, American Industrial Hygiene Association Conference, Las Vegas, NV., May (1985).

Jayjock, M.A. and L. Levin: A NOVEL TECHNIQUE FOR THE MEASUREMENT OF ELECTROSTATIC CHARGE ON PLASTIC DUST AEROSOLS, American Industrial Hygiene Association Conference, Philadelphia, PA., May (1983).

Jayjock, M.A. and L. Levin: HEALTH HAZARDS IN A SMALL AUTOMOTIVE BODY REPAIR SHOP, American Industrial Hygiene Association Conference, Portland, OR. May (1981).

PROFESSIONAL ORGANIZATIONS

U.S. EPA - Office of Pollution Prevention & Toxics - Voluntary Children's Chemical Evaluation Program (VCCEP), Peer Consultation Panel on Flame Retardants, 2003.

US EPA Science Advisory Board, Executive Committee, Human Health Research Strategy Panel, November 2002.

US EPA Science Advisory Board Consultant 2001-2003 - Integrated Human Exposure Committee

US EPA Science Advisory Board Member 1998-2001 - Integrated Human Exposure Committee (IHEC)

National Research Council - National Academy of Sciences
Member: Committee to Review Risk Management in the DOE's Environmental Remediation Program
Committee on Advances in Assessing Human Exposure to Airborne Pollutants
Committee on Toxicology - Subcommittee on Risk Assessment of Flame-Retardant Chemicals.

EPA Technical Review Panel
Member: EPA/Southwest Research Institute: Project: "Engineering and Toxic Characterization Studies and Development of Unit Operations Predictive Models for New Chemicals."

Member Science Program Committee of the Chemical Industry Institute of Toxicology working on State of the Science (STOTS) research needs in risk assessment.

Member of the Peer-Review Panel for the science program at the National Exposure Assessment Laboratory of the US Environmental Protection Agency (US EPA - NERL).

Editorial Board Member - American Industrial Hygiene Journal 1998-2003

American Chemistry Council (formerly Chemical Manufacturers Association)
Former Chairman: Exposure Assessment Task Group of the Health and Safety Committee.
Current Member (Former Chairman): Human Health Exposure Assessment Technical Implementation Panel (TIP) for the Generic Research Program.

Fellow of the American Industrial Hygiene Association

Diplomat of the American Board of Industrial Hygiene (CIH)

American Industrial Hygiene Association:
Committee on Exposure Assessment Strategies
Exposure Strategies Modeling Subcommittee
Exposure Strategies Expert System Subcommittee
Committee on Risk Assessment
Low-Dose Estimation Task Group

Member of the British Occupational Hygiene Society

ASTM member of Committee D22 on Sampling and Analysis of Atmospheres

Governing Board Member of the International Society for Exposure Analysis (ISEA) 1995-1998

President Philadelphia Chapter of Society for Risk Analysis 1993-1994

Councilor for the Philadelphia Chapter of the Society of Risk Analysis 1994-1996

Advisory Board Member for the Drexel School of Environmental Science, Engineering and Policy 1998-2002